CEFABIG-O/S

CEFABIG Oral Suspension

CEFABIG Oral Suspension is an antibiotic medicine containing Cefixime, a third-generation cephalosporin antibiotic used to treat various bacterial infections, particularly in children. It works by inhibiting bacterial cell wall synthesis, helping eliminate infection-causing bacteria. It may be prescribed for infections affecting the respiratory tract, ears, throat, urinary tract, and other parts of the body. This medicine is effective against susceptible bacterial infections but does not work against viral infections such as the common cold or flu.

Composition:

  • Active Ingredient: Cefixime 50 mg
  • Drug Class: Third-Generation Cephalosporin Antibiotic
  • Formulation: Oral Suspension.

Therapeutic Indications:

CEFABIG Oral Suspension is used for the treatment of various bacterial infections caused by susceptible microorganisms, including:

  • Respiratory Tract Infections: Helps treat bacterial infections affecting the respiratory system, including acute exacerbations of bronchitis.
  • Ear Infections (Otitis Media): Used to treat bacterial infections of the middle ear, particularly in children.
  • Throat Infections: Helps manage bacterial infections such as pharyngitis and tonsillitis.
  • Urinary Tract Infections (UTIs): Used for treating uncomplicated bacterial infections affecting the urinary system.
  • Bacterial Infections: May be prescribed for other susceptible bacterial infections based on medical evaluation and antibiotic sensitivity.

Mechanism of Action:

CEFABIG Oral Suspension works by inhibiting bacterial cell wall synthesis. Cefixime binds to penicillin-binding proteins (PBPs), which are essential for the formation and maintenance of bacterial cell walls. This disrupts the cell wall structure, eventually causing bacterial cell death. Its bactericidal action helps eliminate susceptible infection-causing bacteria and supports recovery from bacterial infections.

Dosage and Administration:

  • Pediatric Patients: The dosage is generally calculated according to the child's body weight, age, and severity of infection.
  • Recommended Dosage: A commonly used pediatric cefixime regimen for children aged 6 months and older is 8 mg/kg/day, given once daily or divided into two doses. The treating doctor determines the appropriate dose.
  • Administration: For oral use only. Administer the suspension using a suitable measuring spoon or oral syringe.
  • Reconstitution: Prepare the suspension by adding the recommended amount of water according to the manufacturer's instructions.
  • Treatment Duration: Complete the full prescribed antibiotic course, even if symptoms improve before treatment ends.

Precautions and Warnings:

  • Allergic Reactions: Avoid using this medicine in patients with a known allergy to Cefixime, cephalosporins, or other beta-lactam antibiotics.
  • Kidney Disorders: Inform your doctor if the child has kidney problems, as dosage adjustments may be required.
  • Age Restrictions: Safety and effectiveness in infants younger than 6 months have not been established.
  • Gastrointestinal Disorders: Use with caution in patients with a history of colitis or antibiotic-associated diarrhoea.
  • Drug Interactions: Inform your doctor about other medicines, particularly Carbamazepine, Warfarin, and other anticoagulants.
  • Pregnancy and Breastfeeding: Adults using this medicine should consult their doctor before taking it during pregnancy or breastfeeding.
  • Antibiotic Resistance: Use this medicine only when prescribed and complete the recommended treatment course to reduce the risk of antibiotic resistance.

Possible Side Effects:

Common and reported side effects of CEFABIG Oral Suspension may include:

  • Diarrhoea
  • Nausea and vomiting
  • Loose stools
  • Abdominal pain
  • Indigestion
  • Headache
  • Dizziness
  • Skin rash
  • Itching
  • Allergic reactions

Serious adverse effects may include severe allergic reactions and persistent or severe antibiotic-associated diarrhoea. Seek medical attention if unusual or severe symptoms occur.

Storage:

  • Store the unopened product according to the manufacturer's recommended storage conditions.
  • Keep the medicine away from excessive heat, moisture, and direct sunlight.
  • After reconstitution, store the suspension according to the instructions provided on the product packaging.
  • Shake the bottle well before each use.
  • Do not use the suspension beyond its recommended period after reconstitution.
  • Keep the medicine out of reach of children.

Conclusion:

CEFABIG Oral Suspension (Cefixime 50 mg) is a third-generation cephalosporin antibiotic primarily used for treating various bacterial infections, particularly in pediatric patients. Its antibacterial action works by inhibiting bacterial cell wall synthesis, helping eliminate susceptible infection-causing bacteria. It is commonly prescribed for respiratory tract infections, ear infections, throat infections, and uncomplicated urinary tract infections. The medicine should be used under medical supervision, with dosage determined according to the child's age, body weight, and clinical condition.